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KMID : 0355219900150010009
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Journal of Korean Academy Oral Medicine
1990 Volume.15 No. 1 p.9 ~ p.26
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A Study on the Rheological Property of saliva
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Kho, Hong-Seop/고홍섭
Lee, Sung-Woo/이승우
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Abstract
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The importance of saliva in oral health has come increasingly apparent in expanding aged opulation. Nowadays, advance in medical prodares and utilization of medication have been xmbined in an effort to maintain the quality of fe. However, one of the common sequela to this Qart is an increased prevalence of salivary dysaction and the most common clinical manifes+tion of salivary dysfunction is a decreased "Put of secretion, termed "dry mouth"(hypo. - 4vation, xerostomis, or asialorrhea), which clini14Y may vary from a slight reduction in salivary low with transitory inconvenience to a total aastomia."
Among diverse functions of saliva, lubrication ´ riot only important in facilitating the movements of the tongue and lips during chewing and swallowing but also essential for clearly articulated speech.," Therefore, individuals with diminished salivary gland function are subject to serious alteration of the oral mucosa and may have difficulty with speech, mastication, and deglutition. `-" In addition, high rate of caries susceptibility and attrition of the dentition may be observed.
4-4)
While the many causes of xerostomia and its proper diagnosis have been addressed in the recent literature´s´", two approaches have been utilized for the treatment of dry mouth : intrinsic and extrinsic. " Intrinsic reagents have been used to maintain or augment hypofunctional glands and can include pilocarpine´-"; bromhexine", and anethole-trithione." An obvious disadvantage of this approach is the potential side-effects, and the actual formulation and regimen of these compounds are still under experimental study.´ As a extrinsic reagent, artificial saliva has served as . a replacement modality for individuals exhibiting hyposalivation,´-"?u´ But, most commercially available artificial salivas generally lack the lubricatory protein, macromolecules, and antimicrobial factors found in normal saliva.
The efficacy of saliva as a lubricant will depend
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